The JUVEDERM® family of hyaluronic acid dermal fillers provides a smooth, long-lasting correction of moderate to severe facial wrinkles and folds.

JUVEDERM® is the first smooth consistency gel formulation and only hyaluronic acid dermal filler approved by the FDA to last up to one year from initial treatment.1 JUVEDERM® is developed using the proprietary HYLACROSS technology, an advanced manufacturing process that results in a malleable, smooth gel that flows easily and consistently into the skin and provides a predictable result. All other hyaluronic acid dermal fillers currently on the market have a granular consistency gel. These granules can be seen under 2.4x magnification as opposed to the smooth consistency gel of the JUVEDERM® dermal fillers.

In 2010, the FDA approved JUVEDERM® XC formulated with the local anesthetic lidocaine to provide patients with a more comfortable injection experience when compared to the non-lidocaine formulation, and potentially less time spent in the physician's office. JUVEDERM® Ultra XC and JUVEDERM® Ultra Plus XC contain 0.3% preservative-free lidocaine and numb the treatment area within seconds, potentially reducing the need for an additional anesthetic. JUVEDERM® XC products provide the same smooth, long-lasting results as demonstrated with existing JUVEDERM® products

To provide physicians with the flexibility to tailor each treatment to the specific needs of the patient, the JUVEDERM® family of dermal fillers include JUVEDERM® Ultra and JUVEDERM® Ultra XC with lidocaine, highly cross-linked formulations for more versatility in contouring and volumizing of facial wrinkles and folds; and JUVEDERM® Ultra Plus and JUVEDERM® Ultra Plus XC with lidocaine, more highly cross-linked robust formulations for volumizing and correction of deeper folds and wrinkles.

Ask your doctor if JUVEDERM® is right for you.

A Brief Description of Indications for Use, Contraindications, Warnings, Precautions, and Adverse Events for JUVEDERM® Injectable Gel

Indication: In the United States, JUVEDERM® injectable gel (including JUVEDERM® Ultra, JUVEDERM® Ultra Plus, JUVEDERM® Ultra XC, and JUVEDERM® Ultra Plus XC) is indicated for correction of moderate to severe facial wrinkles and folds (such as nasolabial folds).

Contraindications: JUVEDERM® injectable gel should not be used in patients who have severe allergies marked by a history of anaphylaxis or history or presence of multiple severe allergies. JUVEDERM® should not be used in patients with a history of allergies to Gram-positive bacterial proteins. JUVEDERM® Ultra XC and JUVEDERM® Ultra Plus XC should not be used in patients with a history of allergies to lidocaine.